Clinical Case Report

Postoperative Wound Treatment – February 2016

Important Information About This Case Report
This historical case report describes an individual clinical experience and is provided for healthcare-professional information only. Results may vary and cannot be attributed to LIGASANO® alone. Products and clinical practices described may differ from current U.S. product availability and labeling. Always refer to the applicable current U.S. Instructions for Use. This report does not establish payer coverage, coding, reimbursement, or medical necessity.

February 2016 | Practical Experience Report by Heidi Jodl, Nurse, Wound Manager AZWM and Head of the WZ® Wound Center Augsburg, Germany

Patient Data and Medical History:

A 52-year-old male patient with diabetic foot syndrome had a forefoot amputation on the left side in February 2016. His medical history includes PAD grade 2 on the left, insulin-dependent type 2 diabetes mellitus, polyneuropathy, chronic renal insufficiency following acute renal failure, and a history of alcohol abuse. Additionally, he suffers from hypokalemia, hypocalcemia, hypertensive diabetic nephropathy, and left MCA stroke. Other conditions include arterial hypertension, hyperlipidemia, and nicotine abuse.

Despite hemiparesis on the right side, the patient is mobile with a forefoot offloading shoe with a continuous sole and a compensating sole on the right side. He spent 60 days in inpatient care. Due to the formation of a 1.6 in (4 cm) deep fistula in the medial forefoot area, another amputation or a lower leg amputation was suggested. Concerned about the prospect of extended hospitalization, the patient was transferred to the WZ® Wound Center Augsburg in April. During his hospital stay, the critical colonization was managed with an antiseptic containing octenidine dihydrochloride and 2.0 g phenoxyethanol (Octenisept®) for wound cleaning. The wound was treated with a silver-containing hydrofiber as the filler and an absorbent dressing for coverage, with daily dressing changes due to strong exudation, wound odor, and critical colonization.

Upon admission to the WZ® Wound Center, the wound environment was edematous, reddened, and slightly overheated. Hyperkeratosis was strongly present at the wound margins, particularly spongy in the plantar area. Removal of the spongy hyperkeratosis revealed a fetid odor. The wound bed showed granulating tissue covered with fibrin. The granulation tissue appeared granular but light pink after the fibrin coating was removed. There was a strong, viscous, cloudy exudation. The local therapeutic wound treatment was initially implemented as follows:

Wound cleaning: The wet-dry phase was performed using a wound cleaning solution based on singlet oxygen (NaOCl) and seawater (ActiMaris®). For skin care and to treat the wound environment, a lotion containing water/oil (w/o) with a lipid content of 27% (BL® - BasicLotion) was applied.

Wound filler: a silver-containing hydrofiber with ethylenediaminetetraacetate (Aquacel® Ag + ExtraTM) was used.

Wound coverage: the wound was covered with Zetuvit® plus 4 x 8 in (10 x 20 cm), and fixation was achieved with an elastic bandage with cotton content, combined with a longitudinal and transverse elastic bandage (Tubifast™ blue 2-Way Stretch Technology®).

Dressing changes were performed daily by the nursing service, and a weekly check-up was conducted at the WZ® Wound Center.

After one week, a viscous exudate appeared beneath the Aquacel® Ag + extra™ when the dressing was removed. Due to its thick consistency, it remained between the wound base and the hydrofiber, which could only absorb it to a limited extent. This exudate congestion inhibited granulation tissue growth. Additionally, the discharge of the exudate from the fistula was limited, showing signs of retention. Therefore, the treatment was switched to LIGASANO® White Dressing, sterile (6 x 4 x 0.4 in / 15 x 10 x 1 cm). The fistula was loosely padded dry with a LIGASANO® White Dressing for cavities (39.4 x 0.6 x 0.16 in / 100 x 1.5 x 0.4 cm).

Under continuous local therapeutic measures using the LIGASANO® White Dressing (size 39.4 x 0.6 x 0.16 in resp. 100 x 1.5 x 0.4 cm), the fistula closed, and the amount of exudation was significantly reduced. The wound bed displayed well-perfused, granular granulation tissue with no detectable odor. Additionally, there was a noticeable reduction in hyperkeratosis and maceration.

Summary / Conclusion:

The structure of the LIGASANO® White Dressing enabled focused exudate management and controlled absorbency through vertical redirection. Over the course of treatment, fibrin coverage and exudate decreased and granulation tissue was observed.